Interested in moving your Dehydrogenase program forward, but don’t want the hassle of bringing an assay in-house? BellBrook’s expert scientists have you covered. Our team of biochemical and enzymology expert scientists will work diligently to progress your lead candidates through the early-stages of drug discovery. The best part – we are a small custom shop. We can customize assay conditions to suit your project needs, produce results faster, and you will directly collaborate with one of our expert scientists.
Lead Discovery Services Include:
- Inhibitor Screening – To identify or confirm activity with the target.
- Inhibitor Potency Profiling – Dose-response with target and/or related proteins. Fast IC50 results.
- Mechanism of Action Studies – Kinetic analysis to define the mode of inhibition.
- Inhibitor Screening – To identify or confirm activity with the target.
- Triaging Non-stoichiometric Inhibitors – Run assays under different conditions, such as varying detergent and enzyme concentrations.
- Evaluate Compound-Target Binding – Perform ATPase and unwinding assays to confirm target interaction.
